Vulvovaginal Candidiasis in Pregnancy—Between Sensitivity and Resistance to Antimycotics

Vulvovaginitis with Candida spp. is the most common infection in women and rate increased during pregnancy. Antifungal prescription pregnant continues to present challenges decision must balance risk of fetal toxicity benefits fetus mother. Starting from idea that clotrimazole recommended antifungal candidal vaginitis pregnancy, we tested sensitivity different species other azoles, polyenes, antimetabolites. This retrospective study (January June 2019) assessed 663 hospitalized for various pregnancy-related symptoms which samples phage secretion were taken. The laboratory results confirmed 21% cases, indicating 140 positive mycologic samples. In this study, vaginal candidiasis was mostly related first trimester pregnancy (53.57%,) less last (17.14%). albicans frequent isolated strain accounting 118 followed by 16 strains glabrata 6 cases krusei. highest C. found miconazole (93.2%), while krusei completely resistant polyene low antimetabolites even some such as fluconazole. our higher resistance rates flucytosine found, exhibiting greater than albicans.